Oily skin affects both men and women and results in physical signs such as shiny skin and a lack of radiance, often accompanied by dilated pores. Oily skin is also more prone to developing blemishes. Inspired by recent advances in sebocyte biology, Silab has created Sebocytine, a sebum regulating active ingredient rich in wild rose berry (Rosa canina) flavonoids.
According to the company, Sebocytine at 0.5% limits the differentiation and lipogenesis of human sebocytes cultivated in 2D and 3D models, thereby reducing sebum secretion; it reduces the expression of differentiation markers FADS2 (fatty acid desaturase 2), the enzyme responsible for the production of characteristic lipids of sebum, by 22% and Mucin 1, a marker of terminal sebocyte differentiation, by 43%.
In vivo tests on Caucasian skin show that after 28 days of twice daily treatment in comparison to the placebo, Sebocytine limits sebum secretion by 14.9%, an effect observed in 70% of volunteers. It also reduces the total surface occupied by spots by 23.9%. Tests on Asian skin, carried out in China, show that under the same parameters, the quantity of sebum is reduced by 14.8%. In addition, counting lesions shows a significant decrease in the number of pimples of 20.9%.
