315 Wootton Street
Unit N
NJ 07005
United States

+1 973 988 1075



Sytheon Ltd. is an active ingredient supplier/innovator for the personal care industry since 2006. Sytheon headquarters is located in the US and its European affiliate is in France. Sytheon Ltd. is a well-known and respected innovator supplying the personal care industry with a unique range of proprietary and patented active ingredients. Sytheon is a technology-based customer-driven company and its core advantage comes from strategic partnering with global personal care companies. Markets in the US, Europe, and rest of the world are being served by Sytheon directly or through country/region specific distributors.


The four key value-drivers at Sytheon Ltd. are: Safety-Performance-Differentiation-Stability.

Sytheon owes its success to innovation, adherence to sound-scientific principles and customer service.

Every active ingredient in the Sytheon portfolio is “Built for Performance” and clinically proven to deliver healthier skin.

Each ingredient possesses strong product characterisation and is produced under GMP Guidelines to meet tightly controlled product specifications.

Furthermore, Sytheon produces its products following principles of green-chemistry with minimal impact on the environment and the smallest carbon-footprint possible.

Sytheon develops and offers a wide range of proprietary active ingredients that are scientifically and clinically validated for improving the health and beauty of skin.

Key Personnel

Dr. Ratan K Chaudhuri
Founder, President & CEO

Francois Marchio
COO & Managing Director
Sytheon France

Technologies / New Products / Patents

Sytheon develops and offers a wide range of scientifically and clinically validated ingredients for improving the health and beauty of skin.

Sytheon provides innovative solutions in the areas of: ageing skin, skin protection, problem skin, sun protection, pigmentation control, skin hydration, barrier function, photostabilisation and hair fibre protection.

Sytheon has several publications and issued and pending US and European patents.

Microbiome Friendly 24/7 Prevention & Repair of Photodamage

Acetyl Zingerone (AZ) is a multi-targeted antiaging molecule designed to counteract aging before it happens and to reverse key signs of photo-damaged skin.  AZ prevents skin damage and nurtures skin’s own ability to maintain the integrity of the ECM for optimal health and appearance throughout life.

Key attributes:

  • All-in-one – quencher, antioxidant and selective chelator – first-in-the industry
  • Reduces both immediate and delayed skin damage (↓CPDs) first-in-the industry
  • Placebo controlled clinical studies revealed significant improvement in skin defense and reduction in wrinkle, pigmentation and skin redness in photo-aged skin without using sunscreens
  • Balances skin microbiome diversity
  • Two papers accepted in peer reviewed journals. REACH registered. Patented product.

Synastol TC – Provides holistic solution to pollution and blue light induced skin damage with anti-aging benefits

Terminalia Chebula Edible Fruit Extract is a standardized & defined all-natural anti-aging ingredient. TC provides true “Natural Solutions to Pollution and Blue Light Induced skin- Damage”.

Genome-wide expression responses to TC reveals its benefits to skin stem from multiple responses altering tissue architecture, cutaneous biorhythms, and barrier formation.

Key attributes:

  • Broad-spectrum anti-aging benefits including reversal of protein glycation
  • Reduces formation of reactive oxygen species (ROS, cell-based assays) caused by pollution (urban dust) and blue light
  • Prevents formation of lipid peroxides caused by pollution
  • Reduces pollution induced pro-inflammatory biomarkers IL-6 and IL-8
  • It also minimizes inflammation by inhibiting COX & LOX activity. A paper on genomic and bioinformatics analysis has been submitted for publication in a peer reviewed journal. ECOCERT COSMOS NATURAL. Globally approved.

Sytenol A – Yes, retinol found its match

Yes, Retinol found its match. That is Sytenol A (Bakuchiol). It has all the major benefits of retinol but none of the problems. Bakuchiol was shown in a recent study published in British J Dermatology (2018 Jun 27. doi: 10.1111/bjd.16918) to match the established benefits of retinol.

UC-Davis dermatologists concluded that Bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol. It is all natural, well-defined compound with >99% purity, stable, easy to formulate with, requires no dark room for formulation, can be used during the day and has been shown to stabilize retinol. REACH registered. Patented product.

Synovea HR – The new gold standard in skin lightening

Hexylresorcinol is the New Gold Standard in lightening/even-toning products. Clinically proven to be four-times more effective than Hydroquinone. Also, much superior to kojic acid, licorice ascorbic acid and its derivatives.

Multiple clinical studies with Synovea® HR demonstrated its strong performance in skin brightening and hyper-pigmentation control for all skin color. REACH registered. Patented product. Globally approved. Asyntra SL is a liquid synergistic version of HR composed of Caprylic/Capric triglycerides (and) Hexylresorcinol (and) Ethyl Linoleate. REACH registered. Globally approved.

HydraSynol DOI – A smart lipophilic skin hydrator

Isosorbide Dicaprylate is a smart skin hydrator and barrier builder that intelligently provides optimum hydration based on skin moisture content/deficit. Clinically shown to be very effective in providing long-lasting (>48 hrs.) and controlled skin hydration. Works by stimulating Aquaporin-3, Tight Junction, Desmosomes and Epidermal Differentiating genes/proteins. E-Cadherin up-regulation provides broad-spectrum skin homeostasis. ECOCERT COSMOS Natural. REACH registered. Patented Product.

Synoxyl HSS – Provides a solution to make hawaii-compliant sunscreen

Trimethoxybenzylidene Pentanedione is a breakthrough patented product. Synoxyl HSS is an excellent photostabilizer, provides in-vivo SPF boosting by 50% for both organic and inorganic sunscreens and protects skin by inhibiting up-stream ROS cascade.

Perfect product for developing Octocrylene and Oxybenzone-free broad-spectrum sunscreens. REACH registered. Patented product.

Synactin AC – Designed to alleviate all five key acne targets

Caprylic/Capric triglycerides (and) Ethyl Linoleate (and) Hexylresorcinol is clinically proven to mitigate acne-affected skin.

Synactin AC designed to alleviate all five key acne targets:

  • Hyper-keratinization
  • Bacterial population
  • Sebum control
  • Inflammation
  • Pigmentation
  • REACH registered. Globally approved.

Synovea EL - A smart synergist with multiple skin benefits

EL is a neutral, lipid-soluble form of Linoleic acid (LA) which is an essential fatty acid needed for skin nourishment.

Multiple skin benefits:

  • Maintains stratum corneum acidity
  • Maintains barrier function
  • Decreases sebaceous gland activity
  • Regulates follicular keratinization
  • Inhibits post-inflammatory hyperpigmentation
  • Reduces skin pigmentation
  • ECOCERT COSMOS Natural. REACH registered. Globally approved.

Synoxyl HCP – A versatile solution to color protection

Being lipophilic, it is very difficult to use Synoxyl HSS in water-based systems. Synoxyl® HCP is a solubilized version of Synoxyl HSS in PEG-8, which is easy to use in water-based systems.

Synoxyl HCP is designed to:

  • Protect water-soluble dyes, fragrance and actives from degradation
  • Prevent color fading indoors against fluorescence light
  • Eliminate iron-induced product degradation due to its chelation property which is far superior to commonly used chelating agents like EDTA and EDDS. REACH registered.

Major Markets

Personal & skin care and selective hair care markets

Specialised Services

Develops exclusive customer specific projects in the areas of synthetic and natural compounds, and deliver cost–effective solutions to satisfy customer needs. Provides turn-key solutions to customers for bringing effective products to the market.

Global Capabilities

Sytheon products are marketed all over the world either direct or through country/region specific distributors.


Synovea; Asyntra; Synastol; HydraSynol; Sytenol; Synactin; Synoxyl.