What is Cellike?
Cellike mimics the natural lipid barrier of skin in its composition and structure. The physical structure of Cellike is very similar to the horny layers of skin barrier (Figure 1). The chemical composition of Cellike is similar to the natural components of skin – phosphatidylcholine, triglyceride, cholesterol, and ceramide.
Cellike offers long-lasting skin moisturizing effect through reinforcing the skin’s natural barrier function. Cosmetics with Cellike are more compatible to the physiological properties of skin than the emulsions with oil and water. The multiple layered liposomes with Cellike offer stabilization and efficient penetration of active ingredients into skin.
A. Lamellar structure of skin lipids (electron microscope)
B. Lamellar structure of Cellike (electron microscope)
C. Maltese cross of skin lipids (cross-polarized microscope)
D. Maltese cross of Cellike (cross-polarized microscope)
Clinical studies on hydration and soothing effects of Cellike
Lipids of the stratum corneum (epidermal lipids) play an important role in skin’s barrier function. The composition and structure of these epidermal lipids determine the intactness of skin’s barrier permeability and moisture balance. When the skin’s barrier is disrupted, it is no longer protected from environmental stressors and pollutants. Permanent disruption of the lipid barrier exposes the skin to repetitive stress and this may result in a degenerative process with higher sensitivity for skin incompatible excipients, allergic reactions, and eczema.
The clinical studies indicated that Cellike has ability to recover erythema occurred by 1% SDS treatment (Figure 2). In addition, it showed that Cellike has effect on stratum corneum hydration (Figure 3).
Figure 2. Effects of Cellike on Erythema
Human skin was first treated with 1% SDS to irritate skin, and then both hydrogel and 12.5% Cellike-containing hydrogelwere applied to the irritated skin. As a result, Cellike-containing hydrogel effectively calms the irritated skin.
Figure 3. Effects of Cellike onStratum Corneum Hydration
|INCI NAME||Caprylic/Capric Triglyceride, Hydrogenated Phosphatidylcholine, Butyrospermum Parkii (Shea) Butter, Glycerin, Phytosterols, Glyceryl Caprylate, Ceramide 3, Water|
|COSMETICS USES||Cellike supports the barrier function by mosaic modulating. This means, that the help of skin deficiencies in the lipid barrier. Cellike is successfully used for the supportive prevention of skin disorders such as dry skin, impure skin, acne, neurodermatitis, psoriasis, etc. benefit from the preparations.|
|USE LEVEL||Usage levels may vary from 5% to 50%, depending on the formulation.|
• General Skin Toner: ~5%
• General Lotion: 10%~ 15%
• General Cream: 30 ~ 50%
• For severe eczema: use 100% Cellike directly
|STORAGE & SHELF LIFE||Cellike should be stored in the original container protected from light in a clean place at a room temperature. If stored under the recommended conditions, Cellike remains stable for at least 2 years.|
|OIL HOLDING CAPACITY||Approximately up to 20%|
|SPECIFICATION||Appearance ~ White to off-white colored cream|
Odor ~ Characteristics
Solubility ~ Water-dispersible
pH ~ 3.50 ~ 5.00 ~ 7.00 at 25°C
Specific Gravity ~ 0.90 ~ 1.10 at 25°C
Cellike is a cosmetic ingredient for sensitive skin, can be used in various type of cosmetic application.