Chronogen keeps cell clocks ticking

Published: 21-Aug-2010 Featured companies: Ashland
Ingredients


The latest offering from ISP is an innovative anti-ageing tetrapeptide, inspired by epigenetic science and designed to boost the expression of clock genes. Recent research has shown that cells can independently tell time via a precise molecular mechanism involving the expression and regulation of circadian genes (Clock, Per1, Bmal1, Tim and Cry). These genes give tempo to cells, orchestrating and regulating over 20% of gene expressions, but they can be desynchronised by external factors such as UV radiation.

The bio-engineered tetrapeptide featured in ISP’s Chronogen improves the expression of the proteins involved in the clock mechanism. It helps preserve skin from UV damage during the day and encourages better DNA repair at night, says ISP.

Chronogen is recommended for use in innovative anti-ageing products based on epigenetic science, as well as day and night time formulations.

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Ashland Inc. (NYSE: ASH) is a global additives and specialty ingredients company with a conscious and proactive mindset for environment, social and governance (ESG). The...
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