A sustainable cosmetic ingredient crafted for all complexions, responsibly sourced in Burkina Faso
Givaudan Active Beauty is proud to launch Mangixyl, a powerful microbiome-friendly cosmetic ingredient with proven efficacy targeting oily skin through sebum regulation. Created from responsibly sourced mango leaves and designed with inclusive beauty in mind, this sustainable innovation encapsulates our Company Purpose of ‘creating for happier, healthier lives with love for nature’.
In an era where sustainability and traceability are top of mind for consumers, the sourcing story of Mangixyl highlights our commitment to our company purpose.
The mango leaves are collected in collaboration with the Association Bendia, based in Koro village (Burkina Faso, Africa). The association is a women-led initiative to contribute to the improvement of the living conditions of the community.
Derived from the green fractionation of mango leaves, Mangixyl is a cosmetic innovation able to activate specific receptors of gene’s pathway normally regulated by the highly potent retinoic acid.
To fight against the visible appearance of oily skin, applying mattifying powders in order to absorb sebum is a solution; but it requires many applications during the day, and the amount of product to apply is often visible on the face.
If sometimes the sebum can be perceived as an enemy for the skin appearance, it’s important to keep in mind that its balance is essential. Indeed, the sebum is an essential part of skin health, since it participates to the hydration of the epidermis and contributes to the suppleness and softness of the epidermis.
By crafting Mangixyl, we aim to relieve consumers from the discomfort caused by oily skin. The ingredient activates some receptors of the retinoic acid-regulated genes pathway and decreases the synthesis of lipids on all skin ethnicities.
Reflecting our commitment to inclusive beauty, Mangixyl is a genderless, universal ingredient that is suitable for all age groups and skin tones. To evaluate the benefits of our ingredient, three clinical tests were conducted in double blind versus placebo, on volunteers from different skin complexions: African (South Africa), Asian (China) and Caucasian (Europe).
The measurement of sebum quantity was done on cheeks and nose area at D0 and D28 by sebumeter or sebufix. The tested product was a cream, applied twice a day on the face, containing 1% Mangixyl for Caucasian volunteers and 2% of active for Asian and African volunteers. It appears that Mangixyl significantly reduces, globally twice better than placebo, the quantity of sebum in only in a month for all skin complexions.
This fully natural and microbiome-friendly active ingredient regulates sebum production (down to 15.9% after one month depending on complexion) to relieve the discomfort caused by oily skin – a widespread concern for consumers around the world. Our double-blind tests versus placebo studies have also shown a 49.5% improvement in sebum quality.
Prone-to-acne skin is a multifactorial condition, leading to pimples and irritation, and involving an excess of sebum production. This is why we’ve also tested Mangixyl on several factors related to acne.
During in vitro test, Mangixyl showed a 29% inhibitory action on C. acnes lipase activity.
In the double blind versus placebo clinical study performed on European women with oily skin, a significant reduction by x2.4 of porphyrins intensity is observed (versus placebo) for 80% of volunteers, reflecting the change of C.acnes metabolism on the skin of volunteers, after one month with Mangixyl at 1%.
Relative abundance evolution of different bacterial genera showed that Mangixyl at 1% protected the skin microbiota over time, whereas the placebo group showed a skin dysbiosis.
Mangixyl is the perfect all-round ingredient for creating skin care solutions that not only free consumers from oily skin, but also meet the rising demand for sustainable, traceable and inclusive products.
To inspire the beauty industry, we feature Mangixyl in our new marketing concept called S3D® Womango. Thanks to its three levels of action, this lightweight, mattifying day cream immediately reduces shine, balances sebum production all day long and reduces excess sebum over time – offering consumers a helping hand in their journey towards a clearer complexion.