Givaudan unveils PrimalHyal Ultrafiller an alternative to dermal fillers

Scientists developed a new sustainable hyaluronic acid derivative to protect and rejuvenate the skin

The majority of aesthetic dermal fillers is based on HA and requires local injections with possible complications.

Despite their cost, these fillers cannot restore skin’s natural protection.

Givaudan Active Beauty has developed PrimalHyal Ultrafiller, a new topical hyaluronic acid (HA) acting like an aesthetic filler by penetrating deeply into the skin and filling wrinkles, while stimulating the skin’s anti-pollution defences.

Four clinical tests have demonstrated the consumers’ benefits of PrimalHyal Ultrafiller. With a single application, it fills small wrinkles (-8.7%) in 60 minutes, with further improvement in 6 hours.

After 1 to 2 months it reduces nasogenian wrinkles (-13%) and improves skin texture for 77% of the volunteers. Meanwhile, it reactivates the metabolism of aged skin cells to restore the antioxidant skin defences against daily UV rays and pollution. It also boosts skin antioxidant capacities up to +34%.


Romain Reynaud, R&D Director, said “Our scientific team of skin biology experts have leveraged our leading expertise in hyaluronic acid (HA) to create this new fully acetylated HA. Developed in our Science & Technology Centre of Excellence, PrimalHyal Ultrafiller goes beyond the current HA-based active ingredients already existing in our industry today. We’ve opened a new way of innovation for premium anti-ageing products.”

PrimalHyal Ultrafiller is a patent-pending active ingredient delivering anti-ageing benefits while improving the texture of the skin overall. This innovation will help women and men minimise their wrinkles and enjoy smooth skin full of vitality.

To support the launch of this innovation, Givaudan’s experts have created S3D Pro’Fill: “The time reversing filler”, a new product concept featuring PrimalHyal Ultrafiller.

Inspired by the clinical formulation used during the evaluations of PrimalHyal Ultrafiller, S3D Pro’Fill fluid texture instantly penetrates into each wrinkle resulting in an immediate blur effect.

*PrimalHyal Ultrafiller and S3D Pro’Fill are registered trademark ingredients of Givaudan Active Beauty

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