Hair need to be taken care of to keep it healthy! Laboratoires Expanscience offers several solutions to fight against different hair disorders. Their catalogue includes 3 natural ingredients with proven efficacy adapted to several types of hair issues.
Skinhairgium Bio is obtained from Maca, a peruvian root traditionnaly used for its energizing properties.
It stimulates hair growth by activating the hair growth (=anagen) phase. It does so by activating pathways involved in this phase:
Skinhairgium Bio slows down hair loss by delaying the earlier transition to the catagen phase and increases the proliferation of hair follicle matrix cells.
A biological test notably showed that Skinhairgium at 0,5%, compared to a pharma reference Minoxidil at 1µM, has better results for follicle proportion % staying in anagen phase.
It also boosts adhesion proteins to promote a proper anchorage of hair follicles and hair morphogenesis: b1-Integrin, Laminin-a5 and Fibronectin.
5a-Avocuta acts on the enzyme 5a-reductase, which metabolizes testosterone into dihydrotestosterone, an androgen which induces overproduction of sebum, causing greasy hair and skin.
5a-Avocuta, by inhibiting 5a-reductase, regulates sebum production in order to provide an optimal sebum quantity : formulated at 100 μg/ml, it reduces 5a-reductase activity by 49% in normal human fibroblasts treated for 24h.
It thus appears to be an excellent active substance for improving seborrheic conditions and shows even better results than a pharma reference, Serenoa repens (-35% 5a-reductase activity).
A clinical study was conducted with volunteers who had consulted dermatologists about their problems of greasy hair not solved by existing products on the market: 78% of them noticed a major improvement of the greasy appearance of hair in only 3 weeks!
Laboratoires Expanscience is exploiting all the avocado's treasures to provide a soft and nourishing oil, odourless and totally clear.
This sensorial ingredient, well-known and used in hair care industry, can be formulated in hair shampoo, hair oil, hair care, for its intense nutritive and repairing properties.