RAHN unveils REFORCYL active for mature skin

Published: 20-Nov-2014

Cosmetic ingredients supplier RAHN has developed REFORCYL, an active ingredient to target signs of ageing skin

Cosmetic ingredients supplier RAHN has developed REFORCYL, an active ingredient to target signs of ageing skin.

REFORCYL was specifically developed to regenerate the perturbed barrier of mature skin responsible for decreased elasticity, reduced firmness and the formation of wrinkles, linked to impaired synthesis of epidermal lipids. The active ingredient is based on two plants: Gynostemma pentaphyllum to activate LXR, a skin receptor involved in the synthesis of epidermal lipids; and Cistus incanus to strengthen the reduced antioxidative defence system found in mature skin, neutralising reactive oxygen species which further damage the skin barrier.

A double-blind, placebo-controlled and randomised in-vivo study by the company found that REFORCYL led to enhanced cellular cohesion of the stratum corneum and provided substantial barrier repair after skin damage caused by tape stripping.

RAHN claims that this improvement in barrier strength is mainly due to REFORCYL’s ability to activate epidermal lipid synthesis.

According to the company, the efficacy of REFORCYL has also been proven in several studies: activated LXR in human primary keratinocytes (in-vitro), activated the key enzymes of epidermal lipid synthesis (in-vitro), provided the glue to seal the epidermal barrier (in-vivo study), improved skin hydration, firmness, elasticity and smoothness (in-vivo), visibly improved wrinkle depth in eye area (in-vivo), and perceivably improved the condition of mature skin (controlled user test).

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