Assisting manufacturers to avoid cosmetic derived skin dysbiosis with Cosmetic Microbiome analysis services
During the last couple of years, the connection between skin microbiome and cosmetic use is under thorough study. The skin is colonised by myriads of different microorganisms, with the majority being bacteria while fungi & viruses are also present in lower numbers. Those microorganisms represent the skin microbiome. They form an ecosystem and are usually harmless or may even be beneficial, as they cooperate with the immune system and compete against pathogenic microbes. Antimicrobial activity of cosmetic preservatives and long-term cosmetic usage may disrupt the normal skin microflora. This can lead to dysbiosis, the disruption in the balance of the skin microbiota with adverse effects on the skin. Such effects could be new allergies, skin irritation, discoloration and others.
At QACS, we assist manufacturers avoid cosmetic derived skin dysbiosis with Cosmetic Microbiome analysis services. We support the maintenance of the beneficial skin microflora by using microbiological/molecular methods and clinical trials for Microbiome Friendly and Microbiome Balance claim substantiation. Skin Microbiome studies are supported by years of clinical efficacy testing experience and molecular biology know-how. Studies, adopted to your product’s needs and budget, are provided in the form of customised protocols.
Microbiome Friendly testing reveals information about the product's effect towards the skin microbiome and it is an in vitro study. Competent microbiome friendly in vitro studies are offered in rapid turnaround times to prove that the skin microbiome is not altered significantly by the product during use.
The product is challenged with a complete set of microbes, specific for the skin area in question (face, body, scalp, armpit, foot etc) including the usual pathogens of the area. Also, a solution comprising the total microflora of the specific skin region, swabbed from selected volunteers, is challenged against the formulated product. This gives information regarding product effect on microbial biodiversity of the area. A specially designed algorithm is implemented to score the different parts of the study. Provided that the minimum threshold is achieved, the cosmetic product is deemed as “microbiome friendly” i.e. it does not have any significant effect on skin's microbiome.
If the goal of your product is to retain or restore the natural balance of the skin microbiome, a different approach is used including both in vivo and laboratory testing. As Microbiome Balance studies indicate the alterations cosmetics have on the skin microbiome, trials are more extensive in order to substantiate this specific claim.
Basic package: includes volunteers, microbiological and physiological analyses. The study reveals the effect of your product on the different groups of microbes (like Staphylococcus spp, TAMC and Propionibacterium spp, etc) of selected volunteers during the study period.
Standard package: same as the above including species identification at selected bacterial colonies.
Premium package: includes volunteers, microbiological and physiological analyses along with Next Generation Sequencing (NGS) analysis. This package is the most accurate to reveal the effect of your product on the entire skin microbiome during the study period.
For Cosmetic Microbiome Analysis contact QACS Lab at firstname.lastname@example.org