HerbEx Korean Ginseng Extract for UV Protection and Anti-Wrinkle

Korean Ginseng (Panax ginseng C.A. Meyer) is the most commonly used type of ginsengs.

What is Korean Ginseng ?

Korean Ginseng (Panax ginseng C.A. Meyer) is the most commonly used type of ginsengs. Widely cultivated, Korean Ginseng is now used as a natural preventive and restorative remedy. Korean Ginseng is not only a species different from those of American ginseng or Chinese Sanchi ginseng but grown in an optimal geographical environment and climatic conditions suitable for the growth of ginseng with superior quality. Used for centuries in China, Korean Ginseng was believed to be an anti-aging herb. In addition, Korean Ginseng contains adaptogens that have been known to return the level of our body system back to normal. By equalizing the system levels in the body, Korean Ginseng has been used to lower cholesterol, balance metabolism, increase energy levels, and stimulate the immune system. It has also been used to alleviate fatigue and reduce nervousness and stress on the body. Korean Ginseng also increases oxygenation to the cells and tissues, promoting detoxification as well as stimulating the regeneration of damaged cells. For this reason, Korean Ginseng is the most popular choice these days.

HerbEx Korean Ginseng Extract from BioSpectrum

HerbEx Korean Ginseng Extract was exploited and rectified from natural, fresh ginseng using advanced ultra-hypothermia biotic extraction techniques. The extracts have been analyzed qualitatively and quantitatively to check yield and selectivity of extractions of ginsenosides. As shown in Figure 1, HerbEx Korean Ginseng Extract contains a wide variety of ginsenosides. BioSpectrum has found that HerbEx Korean Ginseng Extract have a variety of biological effects such as UV protection, anti-wrinkle, anti-oxidation, anti-inflammation on human skin.

Figure 1. HPLC profile of ginsenosides in HerbEx Korean Ginseng Extract

HerbEx Korean Ginseng Extract is effective for:

1) UV Protection: UVB damaged skin cells treated with HerbEx Korean Ginseng Extract showed enhanced cell viability by around 50% (Figure 2).

Figure 2. UV Protection effect of HerbEx Korean Ginseng Extract (KGE) measured by MTT assay

2) Anti-Wrinkle: Type I Procollagen and MMP-1 collagenase were increased and decreased, respectively, by HerbEx Korean Ginseng Extract treatment (Figure 3).

Figure 3. Anti-wrinkle effect of HerbEx Korean Ginseng Extract in a dose-dependent manner

Clinical Study on Anti-Wrinkle Effect of HerbEx Korean Ginseng Extract

Anti-wrinkle effect of HerbEx Korean Ginseng Extract was performed in the clinical level and it showed significant anti-wrinkle effect (Figure 4). This clinical study has been performed by DermaPro Skin Research Center using 2% HerbEx Korean Ginseng Extract which contains 0.04% ginsenosides. Skin conditions of fifteen healthy subjects were evaluated before treatment, 4 weeks and 8 weeks after the treatment. Wrinkle on the skin around eye area was evaluated by visual grade, skin roughness (R-parameters), dermal density and self-questionnaires. As a result, we are confident to say that the ginsenosides in the HerbEx Korean Ginseng Extract showed the anti-wrinkle effect as investigated by clinical observation, instrumental assessments, and self-questionnaires.

Figure 4. Anti-wrinkle effect of HerbEx Korean Ginseng Extract on clinical study.

Publication and Patent

[Publication] Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling. Journal of Ethnopharmacology (2007) 109, 29-34.
[Patent] Registration No. 10-076265. Method for producing a ginseng extract containing increased physiological active composition of Rb1, Rb2, Rc, and Rd.

Practical Hints

Product NameHerbEx Korean Ginseng Extract
INCI NameButylene Glycol (ECOCERT, Natural origin), Water, Panax Ginseng Root Extract
DosageRecommended dosage is 2%, but dosage levels can vary from 1% to 5% depending on the types of cosmetic applications.
Formulation GuidelineDo not add when the formulation temperature is higher than 55°C. In the last step, cool the formulation temperature to lower than 55°C and add to the formulation.
Storage & Shelf LifeHerbEx Korean Ginseng Extract should be stored in the original container protected from light in a clean place at a room temperature. If stored under the recommended conditions, it remains stable for at least 3 years before open.
SpecificationAppearance - Yellow Liquid
Odor - Characteristic
Solubility - Water-Soluble
Acid Value (pH) - 6.00-8.00 at 25°C
Specific Gravity - 0.90-1.10 at 25°C
Microbial Analysis - Less than 100 cfu per gram

HerbEx Korean Ginseng Extract from BioSpectrum can be used as an effective cosmetic ingredient for a wide range of cosmetic applications such as UV protection, anti-wrinkle, anti-aging, moisturizing, and skin repair.