Colipa and EU develop liver test simulator

Published: 16-May-2011
Regulatory

New contribution for alternative testing


European cosmetics industry association Colipa and the European Commission are pumping up to €50m into a research project to develop a liver simulating device assessing potential health effects of chronic chemical exposure. This bioreactor will integrate human cells into an artificial matrix, supported by microfluidics and advanced electrodes to reproduce interactions between human liver cells and chemicals for more than one month.

This HeMiBio project (acronym for hepatic microfluidic bioreactor) will help the cosmetics sector reduce animal chronic exposure tests for cosmetic ingredients and produce more accurate results for humans.

“[There is a] great need for suitable human cells to be used in toxicity testing, as there is [often] poor concordance between animal models and toxic effects in humans,” noted the European Commission.

www.hemibio.eu

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