Specifically, the hallmarks of aging are manifestations of key cellular processes that drive cellular degeneration over time. EpiSnow™ targets 7 of these hallmarks:
Epigenetic alterations, genomic instability, deregulated nutrient sensing, cellular senescence, mitochondrial dysfunction, extracellular matrix changes, and the loss of proteostasis. By acting on these cellular mechanisms, EpiSnow™ reverses the aging clock to a younger state, reducing biological age.
In vitro and placebo-controlled in vivo studies have demonstrated that EpiSnow™:
- reduces biological age, calculated according to the Horvath clock
- prevents cellular senescence
- upregulates the expression of the longevity factor Klotho
- stimulates the activation of AMPK under normal and calorie excess conditions
- restores protein expression to a more youthful profile
- upregulates collagens and downregulates metalloproteinases in aged fibroblasts
- visibly reduces photoaging
- reinforces the skin barrier and preserves hydration.
In summary, EpiSnow™ effectively targets the hallmarks of aging. It helps to slow down the epigenetic clock and, therefore, helps in rejuvenating skin appearance.
EpiSnow™
- Reduces biological age in skin cells
- Protects the skin from senescence
- Enhances cellular metabolism
- Supports the epigenetic health of the skin
- Restores evenness for youthful-looking skin
Applications
- Age-defying creams
- Timeless glow concentrates
- Youth preservation shields
- Cellular revive mists
- Barrier rejuvenating serums
Formulating with EpiSnow™
- Recommended use level: 2 – 3 %
- Incorporation: Dissolve EpiSnow™ into the aqueous phase or add pre-solved during the cooling phase (< 60 °C). EpiSnow™ is dissolvable at up to 20 % in water.
- Thermostability: Temperatures of up to 60 °C for a short time do not affect the stability of EpiSnow™.
INCI (EU/PCPC) Declaration
- Coenochloris Signiensis Extract (and) Maltodextrin (and)
- Lecithin (and) Aqua / Water
Additional Information
- Powder form
- Patented (EP2260829 B1, US8206721 B2)
