Lubrizol Unveils Eyeseryl All-In Peptide, a Breakthrough in Eye Contour Rejuvenation

Published: 20-Apr-2026

Where AI Meets Science to Reawaken Tired Eyes. CLEVELAND, Ohio, April 14, 2026 – Pushing the boundaries of skincare innovation, Lubrizol introduces Eyeseryl All-In peptide, a naturally derived, PFAS-free hexapeptide designed to target seven key soft tissues of the eye contour. This advanced multifunctional ingredient helps visibly improve dark circles, eye bags, wrinkles, and other signs of fatigue, delivering a fully rejuvenated eye contour with visible results in just 7 days

A youthful appearance begins with vibrant eyes, the true source of confidence and attractiveness. The eye contour tells a personal story, expressing emotions and reflecting overall wellness. When the eyes appear refreshed and rejuvenated, they project energy, boost self-esteem, and leave a lasting positive impression. Revitalising the eye contour does not only enhance physical appearance; it also transforms the emotions and energy communicated to the world.

Developed at the intersection of AI-enabled discovery and Lubrizol’s deep scientific expertise, Eyeseryl All-In peptide helps deliver a healthier, more refreshed eye appearance. Lubrizol applies artificial intelligence to accelerate and elevate its research—empowering scientists to bring high-performance innovation to market faster.

In vitro studies showed that the peptide attenuated PAR-1 activation and demonstrated efficacy across all seven soft tissues by reducing vascular and lymphatic permeability, as well as melanin and lipid accumulation. It also enhanced key structural and barrier components such as ceramides, collagen type I, collagen type XVIII, and emilin-1, while helping to restore muscle regenerative capacity and ligament strength, in vitro.

In vivo clinical studies conducted across multiple ethnicities confirmed a visibly smoother, refreshed, and rejuvenated eye contour, with significant reductions in puffiness, dark circles, wrinkles, and sagging. Measurable results included:

  • Reduction of malar festoons and upper eyelid volume after 7 days of use
  • Up to 42.9% reduction in eye bag volume and 44.4% reduction in eye bag area
  • Up to 37.3% increase of eye height variation 
  • Smoother‑looking crow’s feet wrinkles after only 7 days, contributing to a more refreshed eye contour

With its unique ability to act on all major eye contour soft tissues and address both visible and biological drivers of ageing, Eyeseryl All-In peptide sets a new standard for comprehensive eye contour care and reinforces Lubrizol’s commitment to cutting-edge, science-backed skincare innovation.

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