Rond Point de Biopole
Biopole Clermont Limagne
Saint Beauzire
F-63360
France
+33 0473339900
Pioneer and expert in ethical biotechnologies for over 30 years, GREENTECH researches, develops and produces high-tech active ingredients from natural sources from the plant, marine and microbial worlds, with respect for people and the environment
At the heart of these ingredients, all of nature's performance, enhanced by cutting-edge processes (bioguided extraction, enzymatic bio-purification, fermentation, bioconversion, etc.), whose bioactivity and clinical efficacy are demonstrated by in vitro studies on skin cells, ex vivo on skin explants and in vivo on human volunteers.
The active cosmetic ingredients developed by GREENTECH are based on major scientific expertise (microbiota, psychobiology/skin-brain axis, exposome, biomimetism) and cover all cosmetic applications for the care, maintenance and protection of the skin, scalp, nails and hair.
GREENTECH encourages a culture of scientific excellence, through the cross-fertilisation of the multidisciplinary expertise of its researchers and through active collaboration with academic and private research.
GREENTECH also cultivates excellence in quality, by complying with the requirements of several standards and certifications required by the international cosmetics market.
KEY FEATURES :
DESCRIPTION :
MYRALYS is a COSMOS-certified organic active ingredient, highly purified in gentiopicroside, sourced from organic wild yellow gentian roots to rejuvenate the upper and lower eye contours. Sustainably and locally harvested in France by gentian-pickers trained in good harvesting practices, gentian roots are strictly selected by GREENTECH scientists based on their gentiopicroside content in order to achieve a highly titrated extract thanks to an advanced purification process.
To counteract eye contour aging, MYRALYS targets 6 interconnected biological pathways according to a multipathway approach. It stimulates NRF2-mediated cell antioxidant response, to limit oxidative stress and oxidation reactions involved in premature skin aging and the formation of advanced glycation end-products (AGEs). MYRALYS also modulates 3 interrelated pathways: it limits inflammation and VEGF-A-mediated angiogenesis while it promotes lymphatic functions by stimulating VEGF-C release. MYRALYS strongly reduces the formation of AGEs, by stimulating Glyoxalase-1 (major detoxifying enzyme which specifically neutralises the highly reactive aldehydes involved in AGEs formation) and by fully neutralising the UV-induced formation of CML (major AGE).
Finally, MYRALYS reduces dermal matrix aging, by strongly stimulating collagen I synthesis and by protecting elastic fibers from UV-induced elastin degradation. Clinically tested on volunteers with aged upper and lower eye contours, MYRALYS lifts droopy upper eyelids (smoother skin, less folds) and rejuvenates under-eye contour by reducing dark circles, eye bags and tear trough severity, with visible and significant results in just 14 days of use (and confirmed after 28 days). MYRALYS is potent natural solution to provide a total eye contour rejuvenation, for a time-defying look.
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
CIRCALYS® is a natural active ingredient titrated in andrographolide sourced from green chiretta (Andrographis paniculata, major ayurvedic detoxifying plant) leaves. CIRCALYS® efficiently reduces the impacts on skin and mood of fatigue induced by modern off-beat life. It rebalances skin rhythms, by restoring an “young” invigorating clock gene expression profile and by acting on circadian modulators related to key cellular pathways.
CIRCALYS® extends cell longevity, reduces cell damages, promoting skin revitalisation. CIRCALYS® also acts as a "Brain-Skin" axis modulator, boosting oxytocin, endocannabinoids and endorphins signalling pathways. Clinically tested on night/shift workers during 28 days, CIRCALYS® was proved to significantly reduce visible signs of fatigue (eye bags, dark circles, under-eye wrinkles, dull tone) and modulate the impacts of fatigue on mood: reduced perceived stress and negative affects, boosted feeling of well-being (“yoga-like” effect).
COSMOS approved and China compliant
DANDRILYS® - Long-Lasting Anti-Dandruff and Scalp Microbiota Modulator
KEY FEATURES:
DESCRIPTION:
DANDRILYS® is a natural active ingredient titrated in saponins (jujubosides) sourced from the bark of the Joazeiro Ziziphus joazeiro (traditionally used as plant-based mild cleanser), acting at multiple levels to efficiently treat dandruff in a long-lasting way. DANDRILYS® targets the scalp microbiota dysbiosis, which is one of the main root causes of dandruff, modulating in vivo both bacteriobiota and mycobiota, towards a healthier scalp.
Clinically, DANDRILYS® 1% is a safe and natural alternative to Zinc Pyrithione (ZPT) 1%, featuring a similar long-lasting anti-dandruff efficacy. It also provides a long-lasting sebum control effect unlike Zinc Pyrithione. DANDRILYS® also reduces the release of histamine (in vitro) to prevent in vivo scalp inflammation, redness and unpleasant itching. DANDRILYS® provides a complete solution against dandruff thanks to a systemic approach, as it modulates both scalp microbiota and biological pathways, for a healthy scalp.
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
ARCOLYS® is a natural active ingredient titrated in Picroside II and polyphenols, extracted from the ayurvedic plant Picrorhiza scrophulariiflora, that restores the natural hair color and reduces hair graying. It targets the mechanisms underlying hair graying (canities): high oxidative stress and loss of active melanocytes in the hair follicle. ARCOLYS® fights against oxidative stress affecting aged graying hair, by activating the expression of antioxidant defences in melanocytes and by reducing ROS in dermal papilla cells.
ARCOLYS® strongly stimulates melanogenesis, under basal condition as well as under oxidative stress condition, leading to hair repigmentation. Clinically tested on volunteers with white hair, ARCOLYS® restores the natural hair color and visibly decreases white hair density from 2.5 months of use. Then, ARCOLYS® offers a holistic approach of hair care, significantly boosting self-esteem by 8% and reducing unpleasant mood by 22% (according to well-recognized psychometric questionnaires), thus emphazing the connection between hair health and individual’s self-representation.
COSMOS approved and China compliant
KEY FEATURES :
DESCRIPTION:
ZORYALYS® is a natural active ingredient designed through a biomimetic approach, combining highly antioxidant and photo protective molecules ( Shogaol and Gingerol from ginger, and Magnolol and Honokiol from magnolia) and long chain fatty acids lipid from pracaxi oil to mimic hair lipids. Thanks to its penetration to the heart of hair, it protects against protein carbonylation, tryptophan & cystine degradation and maintains keratin structure, thus restoring hair strength, shine and
color.
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
EXPOZEN® is a natural active ingredient for sensitive and reactive skin, based on sulfated polysaccharides from Halymenia durvillei, a red alga living off the coast of Madagascar. EXPOZEN® rebalances microbiota of reactive and sensitive skin, especially reducing C. Kroppenstedtii involved in inflammation and redness. It decreases neurogenic inflammation and sensitive skin symptoms : immediate soothing effect, reduction of redness, of heating and flushes sensations. EXPOZEN® also decreases premature aging signs.
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
ACNILYS® is a natural active ingredient titrated in rhodomyrtone, polyphenols and organic acids, sourced from Rose myrtle berries (Rhodomyrtus tomentosa), specifically designed to regulate acne-prone oily skin and acne-related microbiota dysbiosis (focus on C.acnes phylotypes and virulent bacteria).
This potent molecular composition was identified based on Greentech scientists' expertise in ethnopharmacology and pharmacognosy, to target acne-related pathways. ACNILYS® reduces sebogenesis (as proved in an innovative model of iPSC-derived sebocytes) and clinically reduces hyperseborrhea, improving oily skin appearance.
ACNILYS® also limits oxidised squalene-induced inflammation in vitro, preserving sebum quality and thus preventing dyseborrhea. Combined with an inhibitory action on C.acnes-induced inflammation (reduced IL-8 secretion), ACNILYS® reduces skin redness and acne inflammatory lesions as proved in vivo. ACNILYS® regulates acne according to an innovative systemic approach by also addressing acneic skin microbiota dysbiosis. It increases C.acnes phylotype diversity and reduces the abundance of the virulent phylotype IA1. ACNILYS® also decreases the abundance of Cutibacterium granulosum, a poorly known strain even though more virulent than C.acnes. ACNILYS® is a comprehensive innovative solution to achieve a blemish-free and radiant healthy skin.
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
HEBELYS® is an advanced biotechnological active ingredient, designed using a systemic approach, to specifically address skin and emotional needs of the silver generation women and to support women after the age of 50 toward a positive aging, acting like a guardian of their golden age. HEBELYS® provides a sublimating effect on the physical impacts of skin aging (wrinkles, texture, suppleness) and an uplifting effect on mood state (self-esteem, mood).
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
Obtained by an optimised fermentation, BIOTILYS® is a patented active ingredient based on the association of a lysate of the lactic probiotic Lactobacillus pentosus (known to stimulate gut immunity)(parabiotic fraction) and its postbiotic metabolites. BIOTILYS® boosts natural skin defense, by stimulating the expression of antimicrobial peptides (b-defensins, psoriasin, involved in innate immunity and protection against pathogenic bacteria) and by inhibiting the expression of the Toll-like receptor TLR-2 involved in inflammatory response. Like a skin strengthener, BIOTILYS® promotes a healthy skin: it preserves skin microbiota balance, improves skin moisturisation and fortifies skin barrier function.
COSMOS approved and China compliant
KEY FEATURES:
DESCRIPTION:
CANNABIDIOL (CBD) ISOLATE POWDER is a high-grade active ingredient, titrated at 98% minimum in CBD (and ≤ 0.2% THC), obtained by supercritical CO2 extraction and advanced purification, from hemp cultivars authorised by French regulations, grown sustainably in South America and processed locally (high quality sourcing traceability and CSR actions). As a phytocannabinoid with no psychotropic effect, similar to endogenous endocannabinoids, CBD is a biomimetic active. When applied onto skin, it modulates the cutaneous endocannabinoid system as well as other biological pathways, many of which are of interest for the care of combination and oily skin prone to blemishes.
CANNABIDIOL (CBD) ISOLATE POWDER exerts a potent sebostatic effect, by fully inhibiting arachidonic acid-induced sebogenesis (proven in vitro in an innovative iPSC-derived sebocyte model). In vivo, it significantly reduces sebum production by -28% vs placebo after 7 days of daily use. A series of in vitro tests has also shown an effect of CBD ISOLATE in reducing oxidative and inflammatory stress induced by LPS (pro-inflammatory agent mimicking the stress induced by Cutibacterium acnes). It stimulates the synthesis of glutathione (antioxidant peptide constituting a major defense of cells) and limits the production of harmful peroxidized lipids (MDA).
Finally, CBD exerts a potent broad-spectrum anti-inflammatory activity, drastically limiting the secretion of major and minor cytokines in LPS-stressed keratinocytes. CANNABIDIOL (CBD) ISOLATE POWDER is a pure active ingredient ideal for regulating and calming stressed combination to oily skin prone to blemishes, to regain a fresh and harmonious complexion.
COSMOS approved
2022 - BSB Innovation Award - CIRCALYS®
2022 - Wise ingredient Award of Making Cosmetics - MYRALYS
2022 - BSB Innovation Award - MYRALYS
2022 - Innovation Zone Best Ingredient Award - MYRALYS
2022 - Ringier Technology Innovation Award - HEBELYS®
2021 - GDICST Innovation Award - ARCOLYS
2020 - BSB Innovation Award - Organic and Fair for Life Aloe Vera
2020 - BSB Innovation award - EPSILINE
2019 - BSB Innovation Award – INCA INCHI
2018 - BSB Innovation Prize award - URBALYS
2017 - Innovation award Frost and Sullivan - URBALYS
2017 - Healthcare and Life Science – Excellence in plant biotechnology solutions
2017 - GHP Biotechnology award – Best organic pharmaceutical company in Europe
2014 - Award of the French Cosmetic Society (SFC)
2014 - Innovation award Frost and Sullivan - DANDRILYS
2012 - Natrue certification (organic products)
2011 - GMP certification (pharmaceutic)
2010 - ISO 22716 certification (cosmetic GMP)
2002 - Ecocert Certification (organic products)
1997 - Eureka Prize by European Union for GREENTECH’s Innovation level
