New peptide solution for an injection-free way to fuller and firmer skin


New data confirms the benefits of boosting the skin's own hyaluronic acid

In this digital age, with instant access to information, it has never been easier to take control of our well-being and appearance. Although a healthy lifestyle is important, medical beauty procedures also offer an opportunity to explore new limits to achieve the looks we desire. But this doesn't necessarily mean going under the knife.

In 2017, minimally invasive treatments accounted for 80% of plastic surgery procedures in the US and consumers can now choose from a wide range of options, including fillers, peels and laser treatments.

2018: The year of hyaluronic acid?

One of the current most sought-after non-surgical procedures worldwide is cosmetic contouring, i.e. the dermal filler. According to a study from Market Research Future, the largest market for fillers is North America, but their popularity is growing rapidly in the Asia Pacific region and Europe too.

Of the types of filler currently available, the most widely used is hyaluronic acid (HA). The American Society of Plastic Surgeons reports that 78% of dermal filler procedures in the USA use HA. Moreover, because of their natural-looking and reversible results, HA fillers are now the fastest growing non-invasive cosmetic treatment in the US. HA is a very much in-vogue cosmetic ingredient too, with Google trend analytics from May 2018 reporting over 500,000 search results related to the term.

Hyaluronic acid is a naturally occurring substance in humans. 50% of the body's HA is in the skin, where it plays a key role in skin structuring. With age, HA in the dermis decreases, causing facial skin to lose volume in key areas, including the cheeks, under the eyes, the jawline and around the mouth. HA fillers counter this process by plumping up these areas and firming the skin.

Taking the plunge — but without the needle

Dermal fillers give great results but not everyone is keen on needles. DSM's long-established cosmetic ingredient SYN-HYCAN was developed to remodel, lift and volumise facial skin from within by stimulating the body's own production of hyaluronic acid. New data shows just how much this peptide boosts HA synthesis in dermal & epidermal cells in vitro and ex vivo.

Moreover, thanks to cutting-edge 3D visualisation technology and a novel, non-contact compression device, our scientists can now show that SYN-HYCAN significantly improves skin volume and restores firmness across multiple facial areas in vivo.

Visualisation technology is one way of making scientific evidence tangible to consumers, but human feedback on perceivable benefits also makes a difference. Two months after using a 2.5% SYN-HYCAN cosmetic formulation as part of DSM's recent studies, over 87% of panelists reported that their skin felt supple and smooth and nearly 70% confirmed that their skin had more elasticity.

With its scientifically proven volumising and firming benefits for all key facial zones, SYN-HYCAN can be used as an effective cosmetic alternative to dermal fillers or to enhance the effects of HA injections in-between treatments.

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