Protect and renew the skin with a novel calcium delivery system

Published: 11-May-2022

EpiCalsome is a new and effective cosmetic active that is based on an innovative encapsulation technique to treat and protect damaged skin

EpiCalsome™ is a new superior calcium delivery system that protects and renews the skin.

The novel technology encapsulates calcium ions with phospholipids of the highest quality, which makes calcium optimally bioavailable to the skin. Our skin’s epidermis acts as an essential and strong natural barrier that protects our body. In addition to numerous external stressors, ageing and intrinsic metabolic disorders, such as diabetes, impair our skin barrier function, which leads to acute dryness, itching, increased sensitivity, and impaired wound healing.

The loss of the skin’s calcium gradient is a key driver of barrier disruption and skin ageing. Therefore, replenishing the skin’s calcium stores may be a way of combatting the ageing barrier dysfunction.

EpiCalsome™ represents an innovative double cone vector system that encapsulates calcium for a simple and efficient delivery of bioavailable calcium to the skin (patent-pending application).

Watch the explanatory movie here!

In vitro and in vivo studies have demonstrated that EpiCalsome™:

  • improves epidermal barrier function by increasing the expression of important barrier-forming proteins
  • regenerates epidermal barrier formation when calcium levels are low
  • provides immediate and long-term skin protection
  • against harsh irritants
  • accelerates skin recovery and regeneration.

EpiCalsome™ is a new and effective cosmetic active that is based on an innovative encapsulation technique to treat and protect damaged skin. By delivering bioavailable calcium ions, it can help replenish the calcium stores and regenerate the epidermal barrier in aged, diabetic, and extremely dry or atopic skin.


  • Replenishes calcium levels in aged skin
  • Protects and repairs damaged skin
  • Induces faster skin recovery
  • Fortifies delicate skin
  • Prevents skin dryness and irritation


  • Intensive repair creams for extra dry skin
  • Advanced skin-replenishing therapies
  • Pre- and post treatments for stressed and
  • compromised skin
  • Diabetic skin care and dermatoporosis treatments

Formulating with EpiCalsome™

  • Recommended use level: 2-5%
  • Incorporation: EpiCalsome™ can be formulated in emulsions (O / W, W / O) and gels. For cold processes dissolve EpiCalsome™ in the aqueous phase. For cold/hot processes, add during the cooling phase below 40 °C.
  • Thermostability: Homogenization and temperatures of up to 40 °C for a short time will not affect the stability of EpiCalsome™.

INCI (EU / PCPC) Declaration

Hydrogenated Lecithin (and) Calcium Chloride (and)Glycerin (and) Pentylene Glycol (and) Aqua / Water

Additional Information

  • Creamy consistency
  • Without preservation
  • Water-soluble

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