EU scientists challenge anti-ageing effects of sirtuins
Nematode worm evidence re-examined for skin creams
EU funded scientists have debunked assumptions that by promoting production of a protein called sirtuin, anti-ageing creams can keep skin looking young, fresh and wrinkle-free.
Personal care product companies have claimed that sirtuin is activated by the plant-based drug resveratrol. But its effect has now been disputed by research funded from the EU’s PROTEOMAGE and LIFESPAN projects.
Scientists examined the nematode worm, because previous tests had shown longer lived specimens had higher levels of sirtuin. But this time, they took into account all other potential differences between the worms and found that those with an artificially raised production of sirtuin actually lived no longer than control standard worms.
The University of London’s Dr David Gems told a European Commission briefing note: “Sirtuins, far from being a key to longevity appear to have nothing to do with extending life.” He said it was good news, because researchers could now look for a real way of controlling ageing.