L'Oréal-backed biotech firm Debut launches AI ingredient discovery platform

By Alessandro Carrara | Published: 30-Jan-2025

BeautyORB is said to discover novel ingredients and support ‘best-in-class claims’, said the company

L'Oréal-backed biotech firm Debut has released an artificial intelligence (AI)-powered ingredient discovery platform aimed at the beauty industry.

BeautyORB works to discover novel ingredients and support “best-in-class claims” for brands.

It achieves this by screening an estimated 50 billion molecules for their ability to turn on cellular pathways within the skin.

Debut claimed the technology is able to cut down typical screening times of several years and allow the company to create two new ingredients each year.

"With our advanced AI platform and understanding of skin biology, we can rapidly create brand new ingredients through computational compound prediction,” said Joshua Britton, PhD, founder and CEO of Debut.

“This allows us to activate specific aspects of skin biology while also discovering new or improved cellular pathways for enhanced clinical claims.”

The AI platform is said to have already identified three new patented ingredients which include:

  • DermCeutical InflammagePRO, which aids in reducing inflammatory markers, supports the skin barrier and enhances elasticity. 
  • DermCeutical Barrier RepairPRO is an ingredient that protects skin against damage from environmental aggressors. 
  • DermCeutical LongevityPRO claims to decrease markers of cellular senescence and help maintain healthy skin cells.

Debut has also partnered with contract manufacturer KDC/one to create the finished products.

“All this can be done at the click of a button, cutting out years from the innovation cycle and accessing ingredients that no one has seen before,” added Britton.

“We can turn on and off molecular pathways differently and use AI to discover what molecules can affect those pathways.

“The result is a rich, proven and growing pipeline of novel ingredients with the strongest clinical results for our customers, allowing brands to win on product performance rather than marketing.”

L’Oréal recently partnered with IBM to create sustainable cosmetic formulations with generative artificial intelligence (AI).

The French beauty giant will leverage the multinational company’s GenAI technology to uncover new insights into cosmetic formulation data, facilitating its use of sustainable raw materials for energy and material waste reductions.

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