Retinol: Overcoming the hidden challenges of skin care’s hero ingredient

Published: 6-Oct-2025

Retinol is the gold standard in anti-aging skin care, but instability, irritation, and photosensitisation can offset its benefits. Croda explores if encapsulation is the solution

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The delivery of an active substance to its intended biological target is a complex but crucial step in product formulation and is one that can often make the difference between a product showcasing strong clinical results, and one that does not. 

It is typically the case for retinol, whose widely recognised skin benefits are offset by its instability and potential to cause skin irritation and photosensitisation.

One strategy to overcome retinol’s stability issue is encapsulation.

It offers protection by enclosing the active ingredient within a natural-derived, fully biodegradable capsule.

This exclusive carrier system improves both the stability and bioavailability of retinol, enhancing its effectiveness and tolerance in skin care.

A challenging hero ingredient

Retinol (or Vitamin A) is a widely used cosmetic active known for its benefits against skin ageing and photo-induced damage.

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