Sederma helps fragile skin stay strong
Hyaluronic acid is a fundamental part of the extracellular matrix of the dermis. However, it is also present in the active epidermal layers where (with its receptor CD44) it creates a microsphere around keratinocytes, which serves as a molecular reservoir of water and elements necessary for the cutaneous homeostasis. Subliskin, the new ingredient from Sederma, contains specific oligosaccharides that can increase hyaluronic acid synthesis as well as that of elastin and laminin-5.
Hyaluronic acid is a fundamental part of the extracellular matrix of the dermis. However, it is also present in the active epidermal layers where (with its receptor CD44) it creates a microsphere around keratinocytes, which serves as a molecular reservoir of water and elements necessary for the cutaneous homeostasis. Subliskin, the new ingredient from Sederma, contains specific oligosaccharides that can increase hyaluronic acid synthesis as well as that of elastin and laminin-5.
In vivo tests were carried out on 29 female volunteers with lined skin that was thin, dry or fragile. Twice daily application of a 3% Subliskin cream for one month resulted in a 12.3% increase in resistance, a 14.1% increase in density and a 9.1% increase in firmness with a 30% wrinkle reduction (before, above left; after, above right).
