The biological clock is a new target of rejuvenating skin. Ichimaru Pharcos has developed a new natural plant extract as a cosmetic active called CHRONO CHARDY to maintain the skin biological clock.
CHRONO CHARDY reduces wrinkle formation as well as increases skin barrier function, moisture and brightness.
2017 Nobel Prize for Physiology or Medicine was given to the research on biological clock. There are some cosmetic companies has just targeted on the skin clock but Ichimaru Pharcos is the first company discovered that skin barrier function is controlled by skin clock.
Our body has a 24 hour rhythm, from morning to evening and including the sleep cycle. In terms of beauty, a well-adjusted rhythm leads to better skin condition. Well-adjusted skin clock gives the moisture at daytime, the barrier function increases at nighttime as well as collagen production at nighttime.
However, busy lifestyles, mental stress, aging, UV rays, light pollution and irregular life style such as shift work can lead to disruptions of our biological clock.
Ichimaru Pharcos has developed a new natural cosmetic active called CHRONO CHARDY made from chardonnay grape, which is selected by the best result on screening among various sources in terms of the enhancement of skink clock for rejuvenation.
CHRONO CHARDY enhances the action of the clock genes called Period promoting moisture during the day, and BMAL1 improves skin barrier function at night by increasing ceramide transportation.
In addition, CHRONO CHARDY showed induction of COL1A1 mRNA making collagen in dermal fibroblast in the night, and reduced wrinkle formation in the recent human study.
In conclusion, CHRONO CHARDY improves moisture retention in the daytime and stimulates epidermal barrier formation and collagen production in the nighttime by enhancement of biological rhythm, and the all help to maintain beautiful and youthful skin.
CHRONO CHARDY is considered to be a perfect anti-ageing functional raw material, caring for the skin of modern people by enhancing biological clock.
